by Swaraj Thorat | Apr 23, 2025 | Blog
Introduction Eli Lilly’s recent announcement of successful Phase 3 trial results for orforglipron marks a significant milestone in metabolic disease treatment. As the first small molecule oral GLP-1 receptor agonist to complete a Phase 3 trial, orforglipron has...
by Swaraj Thorat | Apr 15, 2025 | Blog
How to Upload Local Scripts to a Specific Folder in a GitHub Repository Use Case: You have a set of files (e.g., .py, .ipynb, etc.) on your local machine and want them to appear inside a specific...
by Swaraj Thorat | Feb 3, 2025 | NGS
Abstract Hypoxia, a condition of reduced oxygen, drives significant changes in prostate cancer progression. This study analyzes the impact of hypoxia on gene expression in two prostate cancer cell lines, LNCaP (androgen-sensitive) and PC3 (androgen-independent), using...
by Swaraj Thorat | Oct 28, 2024 | Rshiny, Blog
Introduction As a student in bioinformatics, I am constantly dealing with data from single-cell RNA sequencing (scRNAseq). Analyzing these large datasets can be challenging, especially when it comes to visualizing and exploring clusters within the data. So, for one of...
by Swaraj Thorat | Oct 27, 2024 | Genomics, Bioinformatics Analysis, Blog
In this project, I explore differential gene expression and pathway enrichment in two prostate cancer cell lines—LNCaP and PC3—under different oxygen conditions: hypoxia (low oxygen) and normoxia (normal oxygen). Hypoxia is a common feature of tumor environments and...
